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Article

Oocyte-specific factors bind a conserved upstream sequence required for mouse zona pellucida promoter activity.

Molecular and cellular biology - 1 Dec 1991

Millar S E, Lader E, Liang L F, Dean J

Abstract excerpt

The zona pellucida of mouse oocytes, composed of three major glycoproteins (ZP1, ZP2, and ZP3), performs crucial functions at fertilization and in early development. The transcripts encoding mouse ZP2 and ZP3 are coordinately expressed and accumulate in oocytes during a 2-week growth phase prior to ovulation. The 5'-flanking regions of mouse Zp-2 and Zp-3 genes and their human homologs contain five short DNA...

Topics

Animals
Base Sequence
Chromosome Deletion
Cloning, Molecular
DNA
DNA-Binding Proteins
Humans
Luciferases
Mice
Molecular Sequence Data
Mutation
Oocytes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Promoter Regions, Genetic

Regulatory Sequences, Nucleic Acid

Sequence Homology, Nucleic Acid

Zona Pellucida

Source

Open in PubMed Open full text

Identifiers

PMID: 1944285
DOI: 10.1128/mcb.11.12.6197-6204.1991
PMCID: PMC361804

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1944285-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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