Article
A systematic review of genes involved in the inverse resistance relationship between cisplatin and paclitaxel chemotherapy: role of BRCA1.
Current cancer drug targets - 1 May 2009
Stordal Britta, Davey Ross
Abstract excerpt
A systematic review of cell models of acquired drug resistance not involving genetic manipulation showed that 80% of cell models had an inverse resistance relationship between cisplatin and paclitaxel. Here we systematically review genetically modified cell lines in which the inverse cisplatin/paclitaxel resistance phenotype has resulted. This will form a short list of genes which may play a role in the mechanism...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
