Article
The G428A nonsense mutation in FUT2 provides strong but not absolute protection against symptomatic GII.4 Norovirus infection.
PloS one - 1 Jan 2009
Carlsson Beatrice, Kindberg Elin, Buesa Javier, Rydell Gustaf E, Lidón Marta Fos, Montava Rebeca, Abu Mallouh Reem, Grahn Ammi, Rodríguez-Díaz Jesús, Bellido Juan, Arnedo Alberto, Larson Göran, Svensson Lennart
Abstract excerpt
In November 2004, 116 individuals in an elderly nursing home in El Grao de Castellón, Spain were symptomatically infected with genogroup II.4 (GII.4) norovirus. The global attack rate was 54.2%. Genotyping of 34 symptomatic individuals regarding the FUT2 gene revealed that one patient was, surpri...
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