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Article

The ‘GGCC’ haplotype of JAK2 confers susceptibility to JAK2 exon 12 mutation-positive polycythemia vera

14 May 2009

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 19440215
DOI: 10.1038/leu.2009.110

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The ‘GGCC’ haplotype of JAK2 confers susceptibility to JAK2 exon 12 mutation-positive polycythemia veraPMID 19440215Read ↗

Prevalance of JAK2 V617F and exon 12 mutations in polycythaemia veraSemantic proximity Read ↗

The JAK2V617F mutation is acquired secondary to the predisposing alteration in familial polycythaemia veraSemantic proximity Read ↗

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Features and Allele Frequency of JAK2 Exon 12-Mutated Polycythemia Vera in Comparison with JAK2V617F-Mutated Disease.Semantic proximity Read ↗

JAK2 46/1 (GGCC) Haplotype: A Biomarker for Oncogenesis, Risk Stratification, and Drug Resistance in Myeloproliferative NeoplasmsSemantic proximity Read ↗

JAK2V617F Exon-14 Mutation Driven Polycythemia Vera.Semantic proximity Read ↗

Familial polycythemia vera with non-germline JAK2(V617F) mutation sparing the abnormal and clonal granulopoiesis.Semantic proximity Read ↗

The C allele of JAK2 rs4495487 is an additional candidate locus that contributes to myeloproliferative neoplasm predisposition in the Japanese population.Semantic proximity Read ↗

The G allele of the JAK2 rs10974944 SNP, part of JAK2 46/1 haplotype, is strongly associated with JAK2 V617F-positive myeloproliferative neoplasms.Semantic proximity Read ↗

Polycythemia vera is not initiated by JAK2 mutationSemantic proximity Read ↗

Fibrotic progression in Polycythemia vera is associated with early concomitant driver-mutations besides JAK2Semantic proximity Read ↗

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