Article
The pivotal regulator GlnB of Escherichia coli is engaged in subtle and context-dependent control.
The FEBS journal - 1 Jun 2009
van Heeswijk Wally C, Molenaar Douwe, Hoving Sjouke, Westerhoff Hans V
Abstract excerpt
This study tests the purported signal amplification capability of the glutamine synthetase (GS) regulatory cascade in Escherichia coli. Intracellular concentrations of the pivotal regulatory protein GlnB were modulated by varying expression of its gene (glnB). Neither glnB expression nor P(II)* (i.e. the sum of the concentration of the P(II)-like proteins GlnB and GlnK) had control over the steady-state...
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