Article
Reduced hypothalamic neurotensin concentrations in the genetically obese diabetic (ob/ob) mouse: possible relationship to obesity.
Metabolism: clinical and experimental - 1 Oct 1991
Williams G, Cardoso H, Lee Y C, Ghatei M A, Flatt P R, Bailey C J, Bloom S R
Abstract excerpt
Hypothalamic tissue levels of nine regulatory peptides (bombesin, calcitonin gene-related peptide [CGRP], galanin, neuromedin B, neuropeptide Y [NPY], neurotensin, somatostatin, substance P, and vasoactive intestinal peptide [VIP]) were compared in Aston obese diabetic (ob/ob) and lean (+/?) mice...
Topics
- Analysis of Variance
- Animals
- Diabetes Mellitus
- Hypothalamus
- Mice
- Mice, Mutant Strains
- Neuropeptides
- Neurotensin
- Obesity
- Osmolar Concentration
- Phenotype
- Reference Values