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Article

Decreased number of simultaneously operating adjacent clusters of replicons in some human strains with and without X-irradiation.

Mutation research - 11 Sept 1998

Barenfeld L S, Nergadze S G, Pleskach N M, Prokofjeva V V, Mikhelson V M

Abstract excerpt

Several parameters of DNA replicons and replicon clusters have been examined using DNA fiber autoradiography in normal vs. mutant human cell lines showing increased chromosomal sensitivity to ionizing radiation as well as radioresistant DNA synthesis. Rates of synthesis of individual replicons for unirradiated ataxia telangiectasia (AT) AT5MO, basal cell naevus syndrome (BCNS) BCN1SP and Down's Syndrome LCH944...

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Identifiers

PMID: 9806420
DOI: 10.1016/s0921-8777(98)00028-7

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