Article
Decreased number of simultaneously operating adjacent clusters of replicons in some human strains with and without X-irradiation.
Mutation research - 11 Sept 1998
Barenfeld L S, Nergadze S G, Pleskach N M, Prokofjeva V V, Mikhelson V M
Abstract excerpt
Several parameters of DNA replicons and replicon clusters have been examined using DNA fiber autoradiography in normal vs. mutant human cell lines showing increased chromosomal sensitivity to ionizing radiation as well as radioresistant DNA synthesis. Rates of synthesis of individual replicons fo...
Topics
- Ataxia Telangiectasia
- Autoradiography
- Basal Cell Nevus Syndrome
- Cell Line
- DNA Replication
- Down Syndrome
- Humans
- Multigene Family
- Mutation
- Radiation Tolerance
- Replicon