Article
Evolution of drug resistance after virological failure of a first-line highly active antiretroviral therapy regimen in Uganda.
Antiviral therapy - 1 Jan 2009
Reynolds Steven J, Kityo Cissy, Mbamanya Frank, Dewar Robin, Ssali Francis, Quinn Thomas C, Mugyenyi Peter, Dybul Mark
Abstract excerpt
BACKGROUND: This study aimed to determine the extent of viral resistance over time among non-clade B HIV type-1-infected patients in Uganda who were maintained on first-line highly active antiretroviral therapy (HAART) following virological failure. METHODS: Genotyping was performed on 16 patients with virological failure who were enrolled in an open-label randomized clinical trial of short-cycle treatment...
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