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Article

Impact of single nucleotide polymorphisms in HBB gene causing haemoglobinopathies: in silico analysis.

New biotechnology - 1 Apr 2009

George Priya Doss C, Rao Sethumadhavan

Abstract excerpt

Single nucleotide polymorphisms (SNPs) are being intensively studied to understand the biological basis of complex traits and diseases. Deleterious mutations of the human beta-globin gene (HBB) are responsible for beta-thalassaemia and other haemoglobinopathies, which are the most common genetic diseases of blood. Single amino acid substitutions in the globin chain are the commonest forms of haemoglobinopathy....

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Source

Identifiers

PMID: 19429541
DOI: 10.1016/j.nbt.2009.01.004

Genes

HBB

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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