Article
WT1 monitoring in core binding factor AML: comparison with specific chimeric products.
Leukemia research - 1 Dec 2009
Lasa Adriana, Carricondo Maite, Estivill Camino, Bussaglia Elena, Gich Ignasi, Brunet Salut, Aventin Anna, Sierra Jorge, Nomdedéu Josep F
Abstract excerpt
Minimal residual disease may help to establish clinical decisions in patients with AML. WT1 offers the possibility to analyze those cases without currently known underlying genetic abnormalities. To compare the value of chimeric specific quantitative PCR with WT1 PCR in CBF acute leukemia, 445 samples from 96 AML (49 AML1-ETO+ and 47 CBFB-MYH11+) cases were included in the study. For each sample AML1-ETO or...
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