Article
Involvement of a common progenitor cell in core binding factor acute myeloid leukaemia associated with mastocytosis.
Leukemia research - 1 Nov 2012
Cornet Edouard, Dumézy Florent, Roumier Christophe, Lepelley Pascale, Jouy Nathalie, Philippe Nathalie, Renneville Aline, Berthon Céline, Nelken Brigitte, Quesnel Bruno, Preudhomme Claude
Abstract excerpt
In core binding factor (CBF) acute myeloid leukaemia (AML), realtime quantitative PCR is useful to quantify the fusion transcript ratio (CBFβ-MYH11 and AML1-ETO, in case of inv(16) and t(8;21) respectively) in peripheral blood and bone marrow during the courses of chemotherapy, in order to monitor minimal residual disease (MRD). In two cases of CBF AML associated with systemic mastocytosis (SM), the persistence...
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