Article
Treating human meniscal fibrochondrocytes with hIGF-1 gene by liposome.
Clinical orthopaedics and related research - 1 Dec 2009
Zhang Hai-ning, Leng Ping, Wang Ying-zhen, Zhang Jie
Abstract excerpt
The menisci are intraarticular fibrocartilaginous structures essential to the normal function of the knee that lack the ability to self-repair. Human meniscal fibrochondrocytes may respond to beneficial genes like human insulin growth factor-1 (hIGF-1) and the meniscal cell may be a feasible donor for gene therapy. To explore this possibility, we amplified the hIGF-1 gene sequence in full length and cloned it...
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