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Article

Apolipoprotein C3 polymorphisms, cognitive function and diabetes in Caribbean origin Hispanics.

PloS one - 1 Jan 2009

Smith Caren E, Tucker Katherine L, Scott Tammy M, Van Rompay Maria, Mattei Josiemer, Lai Chao-Qiang, Parnell Laurence D, Junyent Mireia, Lee Yu-Chi, Garcia-Bailo Bibiana, Ordovás José M

Abstract excerpt

BACKGROUND: Apolipoprotein C3 (APOC3) modulates triglyceride metabolism through inhibition of lipoprotein lipase, but is itself regulated by insulin, so that APOC3 represents a potential mechanism by which glucose metabolism may affect lipid metabolism. Unfavorable lipoprotein profiles and impaired glucose metabolism are linked to cognitive decline, and all three conditions may decrease lifespan. Associations...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19424489
DOI: 10.1371/journal.pone.0005465
PMCID: PMC2674932

Genes

APOC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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