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Article

Hunger and mood during extended fasting are dependent on the GNB3 C825T polymorphism.

Annals of nutrition & metabolism - 1 Jan 2009

Michalsen Andreas, Frey Ulrich H, Merse Stefanie, Siffert Winfried, Dobos Gustav J

Abstract excerpt

BACKGROUND/AIMS: The 825T allele of the G protein beta3-subunit gene (GNB3) is a thrifty genotype associated with an increased risk for obesity. We aimed to determine whether the 825T allele is modifying the subjective response to extended fasting. METHODS: We genotyped 108 subjects who underwent an 8-day modified medical fasting treatment [total energy intake <350 kcal (1465 kJ)/day] for the GNB3 C825T...

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Source

Identifiers

PMID: 19420911
DOI: 10.1159/000217815

Genes

GNB3

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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