Article
N-cadherin in the maintenance of human corneal limbal epithelial progenitor cells in vitro.
Investigative ophthalmology & visual science - 1 Oct 2009
Higa Kazunari, Shimmura Shigeto, Miyashita Hideyuki, Kato Naoko, Ogawa Yoko, Kawakita Tetsuya, Shimazaki Jun, Tsubota Kazuo
Abstract excerpt
PURPOSE: To demonstrate the role of N-cadherin (N-cad) in maintaining the progenitor status of primary human limbal epithelial cells in vitro. METHODS: Immunohistochemistry and immunoelectron microscopy against N-cad was performed in human limbal tissue. The expression of N-cad, cytokeratin (K) 12, and K14 was also observed in primary cultured limbal epithelial cell colonies in 3T3 feeder cells, which also...
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