Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Calpain-mediated N-cadherin proteolytic processing in brain injury.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 6 May 2009

Jang You-Na, Jung Yi-Sook, Lee Soo Hwan, Moon Chang-Hyun, Kim Chang-Hoon, Baik Eun Joo

Abstract excerpt

Neural-cadherin (N-cadherin), a member of the classical cadherin family of transmembrane glycoproteins, mediates cellular recognition and cell-cell adhesion through calcium-dependent homophilic interactions and plays important roles in the development and maintenance of the nervous system. Metalloproteinase is known to cleave N-cadherin, which is further cleaved by gamma-secretase. The intracellular domain of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biotinylation
Share to Brain Injuries

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dizocilpine Maleate

Share to Excitatory Amino Acid Agonists

Share to Excitatory Amino Acid Antagonists

Share to Ionomycin

Share to Ionophores

Share to N-Methylaspartate

Source

Open in PubMed Open full text

Identifiers

PMID: 19420263
DOI: 10.1523/JNEUROSCI.6178-08.2009
PMCID: PMC6665219

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Calpain-mediated N-cadherin proteolytic processing in brain injury.PMID 19420263Read ↗

Characterization of sequential N-cadherin cleavage by ADAM10 and PS1.Semantic proximity Read ↗

Amyloid beta inhibits ectodomain shedding of N-cadherin via down-regulation of cell-surface NMDA receptor.Semantic proximity Read ↗

ADAM-10-mediated N-cadherin cleavage is protein kinase C-alpha dependent and promotes glioblastoma cell migration.Semantic proximity Read ↗

Mice with cleavage-resistant N-cadherin exhibit synapse anomaly in the hippocampus and outperformance in spatial learning tasks.Semantic proximity Read ↗

Oxidative stress-induced MMP- and γ-secretase-dependent VE-cadherin processing is modulated by the proteasome and BMP9/10Semantic proximity Read ↗

Calpain: new perspectives in molecular diversity and physiological-pathological involvement.Semantic proximity Read ↗

Cadherins in neuronal morphogenesis and function.Semantic proximity Read ↗

MST1 mediates the N-methyl-D-aspartate-induced excitotoxicity in mouse cortical neurons.Semantic proximity Read ↗

[The physiological and pathological function of Ca(2 +) -dependent cysteine protease (Calpain) ].Semantic proximity Read ↗

Calpain-Dependent ErbB4 Cleavage Is Involved in Brain Ischemia-Induced Neuronal Death.Semantic proximity Read ↗

TRPM7 regulates cell adhesion by controlling the calcium-dependent protease calpain.Semantic proximity Read ↗

Proteolysis of p53 protein by ubiquitous calpains.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.