Article
Analysis of Taiwanese ichthyosis vulgaris families further demonstrates differences in FLG mutations between European and Asian populations.
The British journal of dermatology - 1 Aug 2009
Hsu C-K, Akiyama M, Nemoto-Hasebe I, Nomura T, Sandilands A, Chao S-C, Lee J Y-Y, Sheu H-M, McLean W H I, Shimizu H
Abstract excerpt
BACKGROUND: Mutations in the gene encoding filaggrin (FLG) were identified to underlie ichthyosis vulgaris (IV) and also shown to predispose to atopic eczema. Until now, no FLG mutations have been described in the Taiwanese population. OBJECTIVES: To elucidate filaggrin mutations in the Taiwanese population and further to clarify the population genetics of filaggrin gene mutations in the Asian populations....
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