Article
Diversity of 23S rRNA genes within individual prokaryotic genomes.
PloS one - 1 Jan 2009
Pei Anna, Nossa Carlos W, Chokshi Pooja, Blaser Martin J, Yang Liying, Rosmarin David M, Pei Zhiheng
Abstract excerpt
BACKGROUND: The concept of ribosomal constraints on rRNA genes is deduced primarily based on the comparison of consensus rRNA sequences between closely related species, but recent advances in whole-genome sequencing allow evaluation of this concept within organisms with multiple rRNA operons. METHODOLOGY/PRINCIPAL FINDINGS: Using the 23S rRNA gene as an example, we analyzed the diversity among individual rRNA...
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