Article
Dombrock genotyping in a native Congolese cohort reveals two novel alleles.
Transfusion - 1 Aug 2009
Chapel-Fernandes Sylvie, Callebaut Isabelle, Halverson Gregory R, Reid Marion E, Bailly Pascal, Chiaroni Jacques
Abstract excerpt
BACKGROUND: Since variant alleles in the Dombrock (DO) blood group system are common in Africans, DNA typing of DO alleles in an uninvestigated Congolese Teke ethnic group was performed. STUDY DESIGN AND METHODS: DO exons were polymerase chain reaction amplified, using genomic DNA extracted from blood samples, and sequenced. Membrane expression in K562 cells transduced with DO-cDNAs using lentiviral vectors was...
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