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Article

SUMO4 Met55Val polymorphism is associated with coronary heart disease in Japanese type 2 diabetes individuals.

Diabetes research and clinical practice - 1 Jul 2009

Shimada Takeshi, Furukawa Yasushi, Furuta Hiroto, Yasuda Kazuki, Matsuno Shohei, Kusuyama Akiko, Doi Asako, Nishi Masahiro, Sasaki Hideyuki, Sanke Tokio, Nanjo Kishio

Abstract excerpt

The Met55Val polymorphism in the small ubiquitin-like modifier 4 (SUMO4) gene has been associated with susceptibility not only to type 1 diabetes, but also to type 2 diabetes and diabetic nephropathy. We tried to confirm the association with susceptibility to type 2 diabetes and to investigate its role in diabetic vascular complications. The polymorphism was genotyped in two independent Japanese samples (Wakayama...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19410319
DOI: 10.1016/j.diabres.2009.04.001

Genes

SUMO4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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SUMO4 Met55Val polymorphism is associated with coronary heart disease in Japanese type 2 diabetes individuals.PMID 19410319Read ↗

[Association between SUMO4 polymorphisms and coronary artery disease with and without type 2 diabetes mellitus].Semantic proximity Read ↗

Polymorphism M55V in gene encoding small ubiquitin-like modifier 4 (SUMO4) protein associates with susceptibility to type 1 (and type 2) diabetes.Semantic proximity Read ↗

A M55V polymorphism in the SUMO4 gene is associated with a reduced prevalence of diabetic retinopathy in patients with Type 1 diabetes.Semantic proximity Read ↗

Association of SUMO4 M55V and -94ins/del gene variants with type-2 diabetes.Semantic proximity Read ↗

SUMO4 163 G>A variation is associated with kidney disease in Indian subjects with type 2 diabetes.Semantic proximity Read ↗

No association of the SUMO4 polymorphism M55V variant in type 2 diabetes in Iranian subjects.Semantic proximity Read ↗

Association between the SUMO4 M55V Polymorphism and Susceptibility to Type 2 Diabetes Mellitus: A Meta-analysis.Semantic proximity Read ↗

SUMO4 M55V variant is associated with diabetic nephropathy in type 2 diabetes.Semantic proximity Read ↗

Small ubiquitin-like modifier-4 Met55Val polymorphism is associated with glycemic control of Type 2 diabetes mellitus in Taiwan.Semantic proximity Read ↗

Association of SUMO4 Met55Val variation with increased insulin resistance in newly diagnosed type 2 diabetes in a Chinese population.Semantic proximity Read ↗

Association of small ubiquitin-like modifier 4 (SUMO4) variant, located in IDDM5 locus, with type 2 diabetes in the Japanese population.Semantic proximity Read ↗

[Association between SUMO4 polymorphisms and type 2 diabetes mellitus].Semantic proximity Read ↗

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