Article
Ethnic and geographical differences in HLA associations with the outcome of hepatitis C virus infection.
Virology journal - 1 May 2009
Wang Jane H, Zheng Xin, Ke Xiaogang, Dorak M Tevfik, Shen Jingjing, Boodram Basmattee, O'Gorman Maurice, Beaman Kenneth, Cotler Scott J, Hershow Ronald, Rong Lijun
Abstract excerpt
BACKGROUND: The association of human leukocyte antigen (HLA) genes with the outcome of hepatitis C virus (HCV) infection may be modified by ethnic and geographical differences. RESULTS: HLA-A, -C, -DRB1 and -DQB1 genotyping were performed in a Midwestern American cohort of 105 HCV infected subjects among which 49 cleared HCV infection and 56 had persistent viral infection. A new protective association of...
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