Article
Hepatitis delta virus cDNA sequence from an acutely HBV-infected chimpanzee: sequence conservation in experimental animals.
Journal of medical virology - 1 Aug 1991
Kos T, Molijn A, van Doorn L J, van Belkum A, Dubbeld M, Schellekens H
Abstract excerpt
Hepatitis delta virus (HDV) RNA was isolated from the serum of a chimpanzee acutely infected with hepatitis B virus (HBV) and superinfected with HDV. Interference of HDV with HBV resulted in decreased HBV DNA levels in the serum. This interference did not change the size of the two HBV specific RNAs present in the liver of the chimpanzee. The complete cDNA sequence of the HDV RNA (5th passage) was determined....
Topics
- Acute Disease
- Animals
- Antigens, Viral
- Blotting, Northern
- Blotting, Southern
- Chronic Disease
- DNA
- DNA, Viral
- Female
- Genetic Variation
- Hepatitis B
