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Genetic, Molecular and Clinical Features of Familial Isolated Pituitary Adenomas

1 Jan 2009

Abstract excerpt

Pituitary adenomas occur in a familial setting in about 5% of all cases, and over half of these are due to multiple endocrine neoplasia type 1 (MEN1) and Carney's complex (CNC). Non-MEN1/CNC familial pituitary tumours of all tumour phenotypes, known as familial isolated pituitary adenomas (FIPA), were first described in the late 1990s. Clinical features of FIPA differ from those of sporadic pituitary adenomas, as...

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PMID: 19407507
DOI: 10.1159/000192448

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