Article
[Familial pituitary adenomas].
Presse medicale (Paris, France : 1983) - 1 Jan 2009
Burlacu Maria Cristina, Tichomirowa Maria, Daly Adrian, Beckers Albert
Abstract excerpt
Familial pituitary adenomas are found in multitumoral syndromes such as multiple endocrine neoplasia type 1 (NEM1) and type 4 (NEM4) and the Carney complex (CNC); it remains at present the only known condition in the category of familial isolated pituitary adenomas (FIPA). Familial adenomas account for 3-5% of all pituitary adenomas. Their pathogenesis is known in part: mutations of the menin gene in NEM1 (80%),...
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