Article
A genome-wide linkage and association scan reveals novel loci for autism.
Nature - 8 Oct 2009
Weiss Lauren A, Arking Dan E, Daly Mark J, Chakravarti Aravinda
Abstract excerpt
Although autism is a highly heritable neurodevelopmental disorder, attempts to identify specific susceptibility genes have thus far met with limited success. Genome-wide association studies using half a million or more markers, particularly those with very large sample sizes achieved through meta-analysis, have shown great success in mapping genes for other complex genetic traits. Consequently, we initiated a...
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