Article
A genome-wide association study of autism reveals a common novel risk locus at 5p14.1.
Annals of human genetics - 1 May 2009
Ma Deqiong, Salyakina Daria, Jaworski James M, Konidari Ioanna, Whitehead Patrice L, Andersen Ashley N, Hoffman Joshua D, Slifer Susan H, Hedges Dale J, Cukier Holly N, Griswold Anthony J, McCauley Jacob L, Beecham Gary W, Wright Harry H, Abramson Ruth K, Martin Eden R, Hussman John P, Gilbert John R, Cuccaro Michael L, Haines Jonathan L, Pericak-Vance Margaret A
Abstract excerpt
Although autism is one of the most heritable neuropsychiatric disorders, its underlying genetic architecture has largely eluded description. To comprehensively examine the hypothesis that common variation is important in autism, we performed a genome-wide association study (GWAS) using a discovery dataset of 438 autistic Caucasian families and the Illumina Human 1M beadchip. 96 single nucleotide polymorphisms...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.