Chronic SIV infection ultimately causes immunodeficiency in African non-human primates

Abstract excerpt

The evolution of HIV infection towards AIDS is relatively constant and immanent, except in a small group of long-term non-progressors, in whom the virus–host equilibrium generates a different pattern of chronic infection. Conversely, African monkeys, the natural reservoir of SIV [1], appear to have developed effective control mechanisms and have already reached a dynamic equilibrium with their lentiviruses,...

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