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In Vitro Germ Cell Differentiation from Cynomolgus Monkey Embryonic Stem Cells

27 Apr 2009

Abstract excerpt

BACKGROUND: Mouse embryonic stem (ES) cells can differentiate into female and male germ cells in vitro. Primate ES cells can also differentiate into immature germ cells in vitro. However, little is known about the differentiation markers and culture conditions for in vitro germ cell differentiation from ES cells in primates. Monkey ES cells are thus considered to be a useful model to study primate gametogenesis...

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PMID: 19399191
DOI: 10.1371/journal.pone.0005338

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