Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Progenitor cell self-renewal and cyclic neutropenia.

Cell proliferation - 1 Jun 2009

Dingli D, Antal T, Traulsen A, Pacheco J M

Abstract excerpt

OBJECTIVES: Cyclic neutropenia (CN) is a rare genetic disorder where patients experience regular cycling of numbers of neutrophils and various other haematopoietic lineages. The nadir in neutrophil count is the main source of problems due to risk of life-threatening infections. Patients with CN benefit from granulocyte colony stimulating factor therapy, although cycling persists. Mutations in neutrophil elastase...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Leukocyte Elastase
Share to Models, Biological
Share to Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neutropenia

Source

Open in PubMed Open full text

Identifiers

PMID: 19397594
DOI: 10.1111/j.1365-2184.2009.00598.x
PMCID: PMC2695843

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Progenitor cell self-renewal and cyclic neutropenia.PMID 19397594Read ↗

Cyclic neutropenia.Semantic proximity Read ↗

Cyclical Neutropenia and Other Periodic Hematological Disorders: A Review of Mechanisms and Mathematical ModelsSemantic proximity Read ↗

New insights into the pathomechanism of cyclic neutropenia.Semantic proximity Read ↗

ELANE mutations in cyclic and severe congenital neutropenia: genetics and pathophysiology.Semantic proximity Read ↗

Neutrophil elastase in cyclic and severe congenital neutropenia.Semantic proximity Read ↗

Differential transcriptional control of hematopoiesis in congenital and cyclic neutropenia patients harboring ELANE mutations.Semantic proximity Read ↗

A comparison of the defective granulopoiesis in childhood cyclic neutropenia and in severe congenital neutropenia.Semantic proximity Read ↗

Mutations in ELA2, encoding neutrophil elastase, define a 21-day biological clock in cyclic haematopoiesis.Semantic proximity Read ↗

Hematopoiesis and its disorders: a systems biology approachSemantic proximity Read ↗

Severe congenital neutropenia and the unfolded protein responseSemantic proximity Read ↗

Mutations in growth factor independent-1 associated with human neutropenia block murine granulopoiesis through colony stimulating factor-1.Semantic proximity Read ↗

Mutations associated with neutropenia in dogs and humans disrupt intracellular transport of neutrophil elastase.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.