A large-scale genome-wide association study of Asian populations uncovers genetic factors influencing eight quantitative traits.

doi:10.1038/ng.357

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Article

A large-scale genome-wide association study of Asian populations uncovers genetic factors influencing eight quantitative traits.

Nature genetics - 1 May 2009

Cho Yoon Shin, Go Min Jin, Kim Young Jin, Heo Jee Yeon, Oh Ji Hee, Ban Hyo-Jeong, Yoon Dankyu, Lee Mi Hee, Kim Dong-Joon, Park Miey, Cha Seung-Hun, Kim Jun-Woo, Han Bok-Ghee, Min Haesook, Ahn Younjhin, Park Man Suk, Han Hye Ree, Jang Hye-Yoon, Cho Eun Young, Lee Jong-Eun, Cho Nam H, Shin Chol, Park Taesung, Park Ji Wan, Lee Jong-Keuk, Cardon Lon, Clarke Geraldine, McCarthy Mark I, Lee Jong-Young, Lee Jong-Koo, Oh Bermseok, Kim Hyung-Lae

Abstract excerpt

To identify genetic factors influencing quantitative traits of biomedical importance, we conducted a genome-wide association study in 8,842 samples from population-based cohorts recruited in Korea. For height and body mass index, most variants detected overlapped those reported in European samples. For the other traits examined, replication of promising GWAS signals in 7,861 independent Korean samples identified...

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PMID: 19396169
DOI: 10.1038/ng.357

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GJA1
SFRP4

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