Article

Meta-Analysis of Transcriptomic Datasets Reveals Key Immune Gene Profiles and Signaling Pathways in Bos taurus

2025-09-15

Abstract excerpt

Understanding immune mechanisms in cattle is vital for improving disease resistance through informed breeding and vaccine development. Meta-analysis enables the integration of multiple transcriptomic studies to identify consistent gene expression patterns and enhance statistical power. In this study, we performed a meta-analysis of four bovine transcriptomic datasets (GSE45439, GSE62048, GSE125964, and GSE247921)...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 84cee31f-78a5-58a5-8c7e-51a0c5fdde6d
DOI: 10.1101/2025.09.13.676061

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Meta-Analysis of Transcriptomic Datasets Reveals Key Immune Gene Profiles and Signaling Pathways in Bos taurusDOI 10.1101/2025.09.13.676061Read

Transcriptomic profiling identifies breed-specific immune signatures of Tuberculosis susceptibility in cattleSemantic proximity Read

Preferential differential gene expression within the WC1.1+ γδ T cell compartment in cattle naturally infected with Mycobacterium bovisSemantic proximity Read

Integrative genomics sheds light on the immunogenetics of tuberculosis in cattleSemantic proximity Read

Integrative genomics sheds light on the immunobiology of tuberculosis in cattleSemantic proximity Read

Integrative genomics of the mammalian alveolar macrophage response to intracellular mycobacteriaSemantic proximity Read

Whole blood transcriptomic analysis of beef cattle at arrival identifies potential predictive molecules and mechanisms that indicate animals that naturally resist bovine respiratory diseaseSemantic proximity Read

RNA-Seq Transcriptome Analysis of Peripheral Blood From Cattle Infected With Mycobacterium bovis Across an Experimental Time CourseSemantic proximity Read

Transcriptomic Insights into Mycobacterium orygis Infection-associated Pulmonary Granulomas Reveal Multicellular Immune Networks and Tuberculosis Biomarkers in Cattle.Semantic proximity Read

Integrative Genomics of the Mammalian Alveolar Macrophage Response to Intracellular MycobacteriaSemantic proximity Read

Integrative population genomics and tissue-specific expression profiling in cattle using whole-genome sequence resources.Semantic proximity Read

Genes and Mechanisms Associated With Experimentally Induced Bovine Respiratory Disease Identified With Supervised Machine Learning Methodology on Integrated Transcriptomic DatasetsSemantic proximity Read

RNA-seq Transcriptional Profiling of Peripheral Blood Leukocytes from Cattle Infected with Mycobacterium bovisSemantic proximity Read