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Article

Indications of carbapenem resistance evolution through heteroresistance as an intermediate stage in Acinetobacter baumannii after carbapenem administration.

Revista do Instituto de Medicina Tropical de Sao Paulo - 1 Jan 2000

Superti Silvana Vargas, Martins Daniela de Souza, Caierão Juliana, Soares Fabiana da Silva, Prochnow Taísa, Zavascki Alexandre Prehn

Abstract excerpt

We describe an in vivo evolution of an antimicrobial profile from susceptibility to full-resistance to carbapenems, with heteroresistance as an intermediate stage, in an Acinetobacter baumannii strain. Heteroresistance was characterized by the growth of sub-populations within the susceptibility halo in both disk-diffusion and Etest. PCRs for the main A. baumannii carbapenemases were negative. The exact resistance...

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Identifiers

PMID: 19390741
DOI: 10.1590/s0036-46652009000200010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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