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Article

Immune and genetic aspects of asthma, allergy and parasitic worm infections: evolutionary links.

Parasite immunology - 1 May 2009

Hopkin J

Abstract excerpt

There are important parallels in the immunobiology of allergy and asthma, and of the human host's response to parasitic worms. Th-2 immune actions with 'weep and sweep' mucosal biology are common to both - pathological in the first and protective in the second. Common up-regulating genetic variants of Th-2 immunity, notably in IL13 and STAT6, predict increased risk of asthma and allergy, but diminished intensity...

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Source

Identifiers

PMID: 19388947
DOI: 10.1111/j.1365-3024.2009.01104.x

Genes

STAT6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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