Article
Possible environmental origin of resistance of Aspergillus fumigatus to medical triazoles.
Applied and environmental microbiology - 1 Jun 2009
Snelders Eveline, Huis In 't Veld Robert A G, Rijs Anthonius J M M, Kema Gert H J, Melchers Willem J G, Verweij Paul E
Abstract excerpt
We reported the emergence of resistance to medical triazoles of Aspergillus fumigatus isolates from patients with invasive aspergillosis. A dominant resistance mechanism was found, and we hypothesized that azole resistance might develop through azole exposure in the environment rather than in azole-treated patients. We investigated if A. fumigatus isolates resistant to medical triazoles are present in our...
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