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Article

The functional role of a conserved loop in EAL domain-based cyclic di-GMP-specific phosphodiesterase.

Journal of bacteriology - 1 Aug 2009

Rao Feng, Qi Yaning, Chong Hui Shan, Kotaka Masayo, Li Bin, Li Jinming, Lescar Julien, Tang Kai, Liang Zhao-Xun

Abstract excerpt

EAL domain-based cyclic di-GMP (c-di-GMP)-specific phosphodiesterases play important roles in bacteria by regulating the cellular concentration of the dinucleotide messenger c-di-GMP. EAL domains belong to a family of (beta/alpha)(8) barrel fold enzymes that contain a functional active site loop (loop 6) for substrate binding and catalysis. By examining the two EAL domain-containing proteins RocR and PA2567 from...

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Identifiers

PMID: 19376848
DOI: 10.1128/JB.00327-09
PMCID: PMC2715702

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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