Article
Regulation of the longevity response to temperature by thermosensory neurons in Caenorhabditis elegans.
Current biology : CB - 12 May 2009
Lee Seung-Jae, Kenyon Cynthia
Abstract excerpt
BACKGROUND: Many ectotherms, including C. elegans, have shorter life spans at high temperature than at low temperature. High temperature is generally thought to increase the "rate of living" simply by increasing chemical reaction rates. In this study, we questioned this view and asked whether the temperature dependence of life span is subject to active regulation. RESULTS: We show that thermosensory neurons play...
Read the complete abstract on PubMedTopics
- Animals
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins
- Cytochrome P-450 Enzyme System
- DNA Primers
- Gene Expression Regulation