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Article

Functional analyses of human and zebrafish 18-amino acid in-frame deletion pave the way for domain mapping of the cerebral cavernous malformation 3 protein.

Human mutation - 1 Jun 2009

Voss Katrin, Stahl Sonja, Hogan Benjamin M, Reinders Joerg, Schleider Elisa, Schulte-Merker Stefan, Felbor Ute

Abstract excerpt

Cerebral cavernous malformations (CCMs) may cause recurrent headaches, seizures, and hemorrhagic stroke and have been associated with loss-of-function mutations in CCM1/KRIT1, CCM2, and CCM3/programmed cell death 10 (PDCD10). The CCM3/PDCD10 amino acid sequence does not reveal significant homolog...

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Source

Identifiers

PMID: 19370760
DOI: 10.1002/humu.20996

Genes

STK25
PDCD10
CCM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19370760-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Functional analyses of human and zebrafish 18-amino acid in-frame deletion pave the way for domain mapping of the cerebral cavernous malformation 3 protein.PMID 19370760Read ↗

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