Article
Association between genetic variant on chromosome 12p13 and stroke survival and recurrence: a one year prospective study in Taiwan.
Journal of biomedical science - 3 Jan 2012
Hsieh Yi-Chen, Seshadri Sudha, Chung Wen-Ting, Hsieh Fang-I, Hsu Yi-Hsiang, Lin Huey-Juan, Tseng Hung-Pin, Lien Li-Ming, Bai Chyi-Huey, Hu Chaur-Jong, Jeng Jiann-Shing, Tang Sung-Chun, Chen Chin-I, Yu Chia-Chen, Chiou Hung-Yi
Abstract excerpt
BACKGROUND: The association between ischemic stroke and 2 single nucleotide polymorphisms (SNPs) on chromosome 12p13, rs12425791 and rs11833579 appears inconsistent across different samples. These SNPs are close to the ninjurin2 gene which may alter the risk of stroke by affecting brain response to ischemic injury. The purpose of this study was to investigate the association between these two SNPs and ischemic...
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