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Chimeric Antigens of<i>Toxoplasma gondii</i>: Toward Standardization of Toxoplasmosis Serodiagnosis Using Recombinant Products

1 Jun 2006

Abstract excerpt

We have evaluated the diagnostic utility of six antigenic regions of the Toxoplasma gondii MIC2, MIC3, M2AP, GRA3, GRA7, and SAG1 gene products, assembled in recombinant chimeric antigens by genetic engineering, in order to replace the soluble, whole-cell tachyzoite extract in serological assays. Serum samples from 100 adults with acquired T. gondii infection and from 30 infants born to mothers with primary...

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PMID: 16757610
DOI: 10.1128/jcm.00237-06

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