Article
Apolipoprotein E gene polymorphism and obesity status in middle-aged men with coronary heart disease.
In vivo (Athens, Greece) - 1 Jan 2000
Kolovou Genovefa D, Anagnostopoulou Katherine K, Kostakou Peggy, Giannakopoulou Vassiliki, Mihas Constantinos, Hatzigeorgiou Georgios, Vasiliadis Ioannis K, Mikhailidis Dimitri P, Cokkinos Dennis V
Abstract excerpt
BACKGROUND: Apolipoprotein (apo) E polymorphism has been associated with coronary heart disease (CHD) and obesity. We aimed to determine whether apoE polymorphism is related to CHD in patients with different body mass index (BMI). PATIENTS AND METHODS: A total of 359 CHD men and 248 healthy controls with BMI <27 kg/m2 were genotyped for the apoE polymorphism. The CHD patients were divided into: normoweight (BMI:...
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