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Article

Diagnosis of NUT Midline Carcinoma Using a NUT-specific Monoclonal Antibody

24 Jun 2009

Abstract excerpt

NUT midline carcinoma (NMC) is a uniformly lethal malignancy that is defined by rearrangement of the nuclear protein in testis (NUT) gene on chromosome 15q14. NMCs are morphologically indistinguishable from other poorly differentiated carcinomas, and the diagnosis is usually made currently by fluorescence in situ hybridization (FISH). As normal NUT expression is confined to testis and ovary, we reasoned that an...

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PMID: 19363441
DOI: 10.1097/pas.0b013e318198d666

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