Article
Matrix metalloproteinase-2 promoter variability in psoriasis.
Archives of dermatological research - 1 Jul 2009
Vasku Vladimir, Bienertova Vasku Julie, Slonková Veronika, Kanková Katerina, Vasku Anna
Abstract excerpt
The expression of matrix metalloproteinase-2 was observed to be significantly upregulated in psoriasis. The aim of this study was to associate the DNA polymorphic variants in MMP-2 promoter gene with psoriasis and/or with psoriasis phenotypes related to psoriasis and comorbid heredity. In the total of 582 Czech Caucasian individuals (386 patients with psoriasis and 196 controls of similar age and sex distribution...
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