All Major Lung Cancer Cell Types Produce Parathyroid Hormone-Like Protein: Heterogeneity Assessed by High Performance Liquid Chromatography*

Abstract excerpt

We examined the production of parathyroid hormone-like protein (PLP) by all major lung cancer cell types, including epidermoid, small cell, and adenocarcinoma. We demonstrated that cell lines derived from each cell type released PLP into culture medium. To determine the predominant species of PLP produced by the cell lines, guanidine hydrochloride extracts were prepared and analyzed for PLP by high performance...

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