Article
Paraoxonase 1 (PON1) L55M and Q192R polymorphisms are not associated with chronic kidney disease in Thai individuals with type 2 diabetes.
International journal of clinical practice - 1 Dec 2021
Nawaka Nantiya, Pansang Pornprapa, Saniwa Afifah, Chaibut Nathanai, Jeenduang Nutjaree
Abstract excerpt
BACKGROUND: Decreased paraoxonase 1 (PON1) activity and PON1 polymorphisms have been found to be associated with chronic kidney disease (CKD) in type 2 diabetes mellitus (T2DM). OBJECTIVE: This study aimed to investigate the association of the PON1 L55M and Q192R polymorphisms with CKD in T2DM, as well as their relationship with PON1 activity. METHODS: A total of 166 T2DM patients, including 83 CKD patients and...
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