Article
Characterization of the allergic T-cell response to Pru p 3, the nonspecific lipid transfer protein in peach.
The Journal of allergy and clinical immunology - 1 Jul 2009
Schulten Véronique, Radakovics Astrid, Hartz Christina, Mari Adriano, Vazquez-Cortes Sonia, Fernandez-Rivas Montserrat, Lauer Iris, Jahn-Schmid Beatrice, Eiwegger Thomas, Scheurer Stephan, Bohle Barbara
Abstract excerpt
BACKGROUND: Pru p 3, the nonspecific lipid transfer protein from peach, is an important plant food allergen that frequently induces systemic reactions. OBJECTIVE: We sought to analyze the allergic T-cell response to Pru p 3. METHODS: PBMCs from Italian and Spanish patients with peach allergy were stimulated with purified natural Pru p 3. Allergen-specific T-cell lines were used to identify T-cell epitopes of Pru...
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