Molecular cloning of plane pollen allergen Pla a 3 and its utility as diagnostic marker for peach associated plane pollen allergy.

doi:10.1111/cea.12721

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Article

Molecular cloning of plane pollen allergen Pla a 3 and its utility as diagnostic marker for peach associated plane pollen allergy.

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 May 2016

Wangorsch A, Larsson H, Messmer M, García-Moral A, Lauer I, Wolfheimer S, Schülke S, Bartra J, Vieths S, Lidholm J, Scheurer S

Abstract excerpt

BACKGROUND: Non-specific lipid transfer proteins (nsLTP) are considered to provoke allergic symptoms to plane tree pollen, which are frequently associated with peach allergy. OBJECTIVE: The objective was to clone the cDNA of plane pollen nsLTP Pla a 3, to characterize IgE-binding and allergenic potency of recombinant Pla a 3 in comparison to its natural counterpart and peach nsLTP Pru p 3. METHODS: Natural...

Topics

Allergens
Amino Acid Sequence
Antigens, Plant
Biomarkers
Cloning, Molecular
Cross Reactions
Food Hypersensitivity
Gene Expression
Histamine Release
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Immunization

Immunoglobulin E

Phenotype

Pollen

Protein Isoforms

Prunus persica

Recombinant Proteins

Source

Open in PubMed

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PMID: 26892183
DOI: 10.1111/cea.12721

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