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Article

Molecular mechanism of transcriptional cascade initiated by the EvgS/EvgA system in Escherichia coli K-12.

Bioscience, biotechnology, and biochemistry - 23 Apr 2009

Itou Junji, Eguchi Yoko, Utsumi Ryutaro

Abstract excerpt

Using an EvgS-active mutant (evgS1) in combination with gene deletions, we clarified the molecular mechanism of the transcriptional cascade of acid resistance and multidrug resistance genes initiated by the EvgS/EvgA two-component system in Escherichia coli, followed by sequential induction of the transcriptional regulators, YdeO and GadE. Overexpression of EvgA, the response regulator of the EvgS/EvgA system, is...

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PMID: 19352034
DOI: 10.1271/bbb.80795

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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