The role of epigenetics in mediating environmental effects on phenotype.

Abstract excerpt

Epigenetics is being suggested as a possible interface between the genetic and environmental factors that together give rise to phenotype. In mice there exists a group of genes, known as metastable epialleles, which are sensitive to environmental influences, such as diet, and undergo molecular changes that, once established, remain for the life of the individual. These modifications are epigenetic and in some...

Topics

• Animals
• Chromosomal Instability
• Diet
• Environment
• Epigenesis, Genetic
• Health Status
• Humans
• Life Style
• Mice
• Mice, Transgenic
• Phenotype