Article
Transience of MHC Class I-restricted antigen presentation after influenza A virus infection.
Proceedings of the National Academy of Sciences of the United States of America - 21 Apr 2009
Mintern Justine D, Bedoui Sammy, Davey Gayle M, Moffat Jessica M, Doherty Peter C, Turner Stephen J
Abstract excerpt
Antigen expressed as MHC Class I glycoprotein (pMHCI) complexes on dendritic cells is the primary driver of CD8(+) T cell clonal expansion and differentiation. As we seek to define the molecular differences between acutely stimulated cytotoxic T lymphocyte (CTL) effectors and long-lived memory T...
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