Article
Premorbid adjustment: a phenotype highlighting a distinction rather than an overlap between schizophrenia and bipolar disorder.
Schizophrenia research - 1 May 2009
Rietschel Marcella, Georgi Alexander, Schmael Christine, Schirmbeck Frederike, Strohmaier Jana, Boesshenz Katja V, Schwarz Markus, Nöthen Markus M, Schulze Thomas G
Abstract excerpt
BACKGROUND: Premorbid adjustment (PMA) in schizophrenia (SZ) has been widely studied and shown to be worse in individuals who develop SZ as compared to controls. It has been proposed as a predictor of clinical presentation and outcome, and may delineate a specific SZ phenotype for genetic and other biological studies. Research into PMA in BD has been scarce and inconclusive. AIMS: The authors compared PMA in...
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